BiOptimizers Magnesium Breakthrough Supplement 4.0 - Has 7 Forms of Magnesium: Glycinate, Malate, Citrate, and More - Natural Sleep and Brain Supplement - 60 Capsules

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While also helpful for the heart, magnesium orotate is believed to be the best form for metabolic improvements. This makes it a favourite for athletes seeking enhanced recovery, energy and performance. Sucrosomial Magnesium can bypass the intestinal barrier with more effectiveness than other magnesium forms like Magnesium Citrate, Oxide, or Bisglycinate. This allows for a higher concentration of Magnesium in the body. Zhang Y, Xun P, Wang R, Mao L, He K. Can Magnesium Enhance Exercise Performance?. Nutrients. 2017;9(9):946. Published 2017 Aug 28. doi:10.3390/nu9090946 Takaya J, Higashino H, Kobayashi Y. Intracellular magnesium and resistance. Magnes Res. 2004;17(2):126-136. When you take magnesium in the morning, it supports brain function and stress response throughout the day. In the evening, high doses of magnesium promote relaxation and may help with sleep. Therefore, it is best to divide your magnesium supplement doses throughout the day. If that is not possible, take whenever you can.

Almost half of all Americans do not receive sufficient magnesium from their diet [1] Magnesium. National Institutes of Health. Accessed 7/5/2023. , thanks in part to the consumption of refined foods, which undergo processing that diminishes their magnesium content, and the deterioration of soil quality. de Baaij JH, Hoenderop JG, Bindels RJ. Magnesium in man: implications for health and disease. Physiol Rev. 2015;95(1):1-46. doi:10.1152/physrev.00012.2014 Melhora a Qualidade do Sono. Em um pequeno ensaio clínico envolvendo 46 idosos com insônia,[17] 500 mg de suplemento diário de magnésio reduziram os escores de insônia, latência do sono e cortisol. Os indivíduos também tinham mais melatonina sérica, dormiam mais profundamente e eram menos propensos a acordar no meio da noite. Castiglioni S, Cazzaniga A, Albisetti W, Maier JA. Magnesium and osteoporosis: current state of knowledge and future research directions. Nutrients. 2013;5(8):3022-3033. Published 2013 Jul 31. doi:10.3390/nu5083022Asemi Z, Karamali M, Jamilian M, et al. Magnesium supplementation affects metabolic status and pregnancy outcomes in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Am J Clin Nutr. 2015;102(1):222-229. doi:10.3945/ajcn.114.098616 Reddy P, Edwards LR. Magnesium Supplementation in Vitamin D Deficiency. Am J Ther. 2019;26(1):e124-e132. doi:10.1097/MJT.0000000000000538 Barragán-Rodríguez L, Rodríguez-Morán M, Guerrero-Romero F. Efficacy and safety of oral magnesium supplementation in the treatment of depression in the elderly with type 2 diabetes: a randomized, equivalent trial. Magnes Res. 2008;21(4):218-223.

Takaya J, Higashino H, Kobayashi Y. Intracellular magnesium and resistance. Magnes Res. 2004;17(2):126-136 Sartori SB, Whittle N, Hetzenauer A, Singewald N. Magnesium deficiency induces anxiety and HPA axis dysregulation: modulation by therapeutic drug treatment. Neuropharmacology. 2012;62(1):304-312. doi:10.1016/j.neuropharm.2011.07.027 The most bioavailable version is BiOptimizers Malate, which users normally find in the fruits that they eat. It provides the tartness of this produce, and it is incredibly helpful to individuals who are dealing with migraines or chronic pain. Some studies show that it can help with pain and depression as well.

To boost mood and promote a healthy stress response, it is best to use a combination of forms of magnesium combined with vitamin B6. Studies have confirmed that magnesium with organic acid salt (e.g. citrate and malate) or amino acids (e.g. taurate, glycinate, and sucrosomial) are significantly better absorbed than inorganic salts (oxide, chloride, and sulfate). Also, these different forms are absorbed into different tissues, with taurate, malate, and citrate being the most beneficial for the nervous system

DiNicolantonio JJ, Liu J, O'Keefe JH. Magnesium for the prevention and treatment of cardiovascular disease. Open Heart. 2018;5(2):e000775. Published 2018 Jul 1. doi:10.1136/openhrt-2018-000775It is absolutely essential in the metabolism of macronutrients, as well as the utilization of other minerals, B-complex vitamins, vitamin C and vitamin E. Magnesium Breakthrough offers all 7 forms of magnesium, and is designed to transform your stress and performance. Magnesium aids in maintaining normal heart rhythm and reduces your stress levels so you feel relaxed and at peace. Magnesium is also fundamental to immune health, and is a cofactor in more than 300 enzymatic processes in the body. Bioptimizers Magnesium contains seven different magnesium forms that are easily absorbed by the body and provide a variety of health benefits. The presence of magnesium taurate aids in the improvement of heart health. Overall, magnesium deficiencies tend to exacerbate or increase the risk of conditions that involve chronic inflammation. Moslehi N, Vafa M, Rahimi-Foroushani A, Golestan B. Effects of oral magnesium supplementation on inflammatory markers in middle-aged overweight women. J Res Med Sci. 2012;17(7):607-614.